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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-RQ7265 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. MPG (N-methylpurine-DNA glycosylase) also... more
Product information "Anti-DNA-3-methyladenine glycosylase / MPG / AAG"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. MPG (N-methylpurine-DNA glycosylase) also known as MDG, 3-METHYLADENINE DNA GLYCOSYLASE, 3MeAde DNA GLYCOSYLASE, AAG and APNG is a protein expressed in all cell lines and tissues examined, but was found at particularly high levels in a colon adenocarcinoma cell line(HT29). The completely characterized human MPG gene was found to span 7 to 8 kb of genomic DNA and to be localized 75 kb upstream of the embryonic zeta-globin gene. To assess the contribution of Apng to the repair of several mutagenic lesions in vivo,Hang et al.(1997)biochemically analyzed cell-free extracts of tissues from mice with a targeted deletion of the Apng gene. Following treatment with DNA-methylating agents, increased persistence of 7-methylguanine (meG) was found in liver sections of APNG knockout mice in comparison with wildtype mice, demonstrating an in vivo phenotype for the APNG-null animals. Protein function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3- methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions. [The UniProt Consortium]
Keywords: | Anti-MPG, Anti-AAG, Anti-ADPG, EC=3.2.2.21, Anti-3-alkyladenine DNA glycosylase, Anti-N-methylpurine-DNA glycosylase, Anti-DNA-3-methyladenine glycosylase, Anti-3-methyladenine DNA glycosidase, DNA-3-methyladenine glycosylase Antibody / MPG / AAG |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | RQ7265 |
Properties
Application: | WB, Direct ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | recombinant human protein (amino acids Q20-A298) |
Format: | Purified |
Database Information
KEGG ID : | K03652 | Matching products |
UniProt ID : | P29372 | Matching products |
Gene ID | GeneID 4350 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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