Anti-DLL4 (C-Terminal Region)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-F54133-0.05ML	50 µl		-	-	3 - 10 business days*		326.00€
NSJ-F54133-0.2ML	200 µl		-	-	3 - 10 business days*		702.00€

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In 1X PBS, pH 7.4, with 0.09% sodium azide. Delta-like protein 4 is involved in the Notch... more

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Product information "Anti-DLL4 (C-Terminal Region)"

In 1X PBS, pH 7.4, with 0.09% sodium azide. Delta-like protein 4 is involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate. [UniProt] Protein function: Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate (PubMed:17728344). [The UniProt Consortium]

Keywords:	Anti-DLL4, Anti-Delta4, Anti-Delta-like protein 4, Anti-Drosophila Delta homolog 4, DLL4 Antibody (C-Terminal Region)
Supplier:	NSJ Bioreagents
Supplier-Nr:	F54133

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	A portion of amino acids 608-641 from human DLL4
Format:	Purified