Anti-DLD

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA044849.25 25 µl -

7 - 10 business days*

300.00€
ATA-HPA044849.100 100 µl -

7 - 10 business days*

421.00€
 
Protein function: Lipoamide dehydrogenase is a component of the glycine cleavage system as well... more
Product information "Anti-DLD"
Protein function: Lipoamide dehydrogenase is a component of the glycine cleavage system as well as an E3 component of three alpha-ketoacid dehydrogenase complexes (pyruvate-, alpha-ketoglutarate-, and branched- chain amino acid-dehydrogenase complex) (PubMed:15712224, PubMed:16442803, PubMed:16770810, PubMed:17404228, PubMed:20160912, PubMed:20385101). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion (PubMed:29211711). A fraction of the 2- oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A (PubMed:29211711). In monomeric form may have additional moonlighting function as serine protease (PubMed:17404228). Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98% and to rat: 98%
Keywords: Anti-DLD, Anti-GCSL, Anti-Dihydrolipoamide dehydrogenase, Anti-Glycine cleavage system L protein, Anti-Dihydrolipoyl dehydrogenase, mitochondrial
Supplier: Atlas Antibodies
Supplier-Nr: HPA044849

Properties

Application: WB, IHC, ICC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: DVVAGPMLAH KAEDEGIICV EGMAGGAVHI DYNCVPSVIY THPEVAWVGK SEEQLKEEGI EYKVGKFPFA ANSRAKTNAD TDGMVK (ATA-APrEST83968)

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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