Anti-DIS3L2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA035796.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA035796.100	100 µl		-		7 - 10 business days*		446.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their... more

Close menu

Product information "Anti-DIS3L2"

Protein function: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 76% and to rat: 75%

Keywords:	Anti-FAM6A, Anti-hDIS3L2, Anti-DIS3-like exonuclease 2
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA035796

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: RNRALNGDLV VVKLLPEEHW KVVKPESNDK ETEAAYESDI PEELCGHHLP QQSLKSYNDS PDVIVEAQFD GSDSEDGHGI TQNVLVDGVK KLS (ATA-APrEST87139)