Anti-Desmoglein-1 (DSG1) Monoclonal Antibody (Clone: 18D4)

Anti-Desmoglein-1 (DSG1) Monoclonal Antibody (Clone: 18D4)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-36-2173-20 20 µg -

3 - 11 business days*

375.00€
ABE-36-2173-100 100 µg -

3 - 11 business days*

853.00€
 
Recognizes a protein of ~150kDa, identified as Desmoglein-1 (DSG1). Desmoglein-1 is a member of... more
Product information "Anti-Desmoglein-1 (DSG1) Monoclonal Antibody (Clone: 18D4)"
Recognizes a protein of ~150kDa, identified as Desmoglein-1 (DSG1). Desmoglein-1 is a member of the desmosomal cadherin family.Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms.Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity. Protein function: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. [The UniProt Consortium]
Keywords: Anti-DG1, Anti-DGI, Anti-DSG1, Anti-CDHF4, Anti-Desmoglein-1, Anti-Cadherin family member 4, Anti-Desmosomal glycoprotein 1, Anti-Pemphigus foliaceus antigen, Anti-Desmoglein-1 (DSG1) Monoclonal Antibody (Clone: 18D4)
Supplier: Abeomics
Supplier-Nr: 36-2173

Properties

Application: FC, IF, WB
Antibody Type: Monoclonal
Clone: 18D4
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Human desmoglein-1 intracellular domain

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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