Anti-Deoxyuridine triphosphate nucleotidohydrolase (dUTPase, dUTP pyrophosphatase)

Anti-Deoxyuridine triphosphate nucleotidohydrolase (dUTPase, dUTP pyrophosphatase)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
144464.100 100 µg - -

3 - 19 business days*

659.00€
 
Deoxyuridine triphosphate nucleotidohydrolase (dUTPase) is responsible for maintaining low... more
Product information "Anti-Deoxyuridine triphosphate nucleotidohydrolase (dUTPase, dUTP pyrophosphatase)"
Deoxyuridine triphosphate nucleotidohydrolase (dUTPase) is responsible for maintaining low intracellular levels of dUTP, thus preventing the incorporation of dUTP into DNA. dUTPase activity/expression can be down-regulated using siRNA specifically targeted to dUTPase mRNA and dUTPase plays a role in DNA nucleotide metabolism. This protein, present predominantly in the cytoplasm, contains 252 amino acids with a Mr of 26,704. It exhibits 35% identity with the E. coli dUTPase and 53% identity with the Saccharomyces cerevisiae enzyme. The nuclear and mitochondrial forms of dUTPase are encoded by the same gene with isoform-specific transcripts arising through the use of alternative 5-prime exons. Human dUTPase exhibits 92% identity with rat. Moreover, this enzyme has profound effects on the efficacy of agents that target thymidylate biosynthesis. UniProt Number: P33316, Gene ID: DUT, Applications: Suitable for use in Western Blot and Immunohistochemistry (Paraffin). Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Handling: Store at -20?C for one year. After reconstitution, store at 4?C for one month. Can also be aliquoted and stored frozen at -20?C for long term., Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: 144464

Properties

Application: IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Format: Affinity Purified

Database Information

UniProt ID : P33316 | Matching products

Handling & Safety

Storage: vT
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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