Anti-DDX5

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A300-523A-T 20 µl (2 blots) -

3 - 9 business days

125.00€
A300-523A-M 100 µl (10 blots) -

3 - 9 business days

290.00€
A300-523A 100 µl (20 µg) -

3 - 9 business days

430.00€
 
Protein function: Involved in the alternative regulation of pre-mRNA splicing, its RNA helicase... more
Product information "Anti-DDX5"
Protein function: Involved in the alternative regulation of pre-mRNA splicing, its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation, the function is independent of the RNA helicase activity. Transcriptional coactivator for estrogen receptor ESR1 and androgen receptor AR. Increases ESR1 AF-1 domain-mediated transactivation and ESR1 AF-1 and AF-2 domains transcriptional synergistic activity. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 transcriptional activity and involved in skeletal muscle differentiation. Transcriptional coactivator for p53/TP53 and involved in p53/TP53 transcriptional response to DNA damage and p53/TP53-dependent apoptosis. Transcriptional coactivator for RUNX2 and involved in regulation of osteoblast differentiation. Acts as transcriptional repressor in a promoter-specific manner, the function probably involves association with histone deacetylases, such as HDAC1. As component of a large PER complex is involved in the inhibition of 3' transcriptional termination of circadian target genes such as PER1 and NR1D1 and the control of the circadian rhythms. [The UniProt Consortium]
Keywords: Anti-DDX5, Anti-G17P1, EC=3.6.4.13, Anti-RNA helicase p68, Anti-DEAD box protein 5, Anti-Probable ATP-dependent RNA helicase DDX5
Supplier-Nr: A300-523A-T

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse (Expected: Orangutan, Chimpanzee)
Immunogen: synthetic peptide. The epitope recognized by A300-523A-T maps to a region between residue 575 and the C-terminus (residue 614) of human DEAD (Asp-Glu-Ala-Asp) Polypeptide 5 using the numbering given in entry NP_004387.1 (GeneID 1655).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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