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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES9435.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES9435.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this... more
Product information "Anti-DDX42"
This gene encodes a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008], Protein function: ATP-dependent RNA helicase. Binds to partially double- stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis- stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Cytoplasm . Nucleus ., [Isoform 2]: Nucleus, Cajal body . Nucleus speckle .
Keywords: | Anti-RNAHP, Anti-RHELP, Anti-SF3b125, Anti-DEAD box protein 42, Anti-SF3b DEAD box protein, Anti-RNA helicase-like protein, Anti-RNA helicase-related protein, Anti-ATP-dependent RNA helicase DDX42, Anti-Splicing factor 3B-associated 125 kDa protein, DDX42 |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES9435 |
Properties
Application: | WB, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Synthesized peptide derived from human protein . at AA range: 850-930 |
MW: | 103 kD |
Format: | Purified |
Database Information
KEGG ID : | K12835 | Matching products |
UniProt ID : | Q86XP3 | Matching products |
Gene ID | GeneID 11325 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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