Anti-Dachshund homolog 2 / DACH2, Internal

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG64479.100	100 µg		-	-	6 - 14 business days*		784.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Transcription factor that is involved in regulation of organogenesis. Seems to... more

Close menu

Product information "Anti-Dachshund homolog 2 / DACH2, Internal"

Protein function: Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator for SIX1 and SIX6. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. Is recruited with SIX6 to the p27Kip1 promoter in embryonal retina. SIX6 corepression seems also to involve NCOR1, TBL1, HDAC1 and HDAC3. May be involved together with PAX3, SIX1, and EYA2 in regulation of myogenesis. In the developing somite, expression of DACH2 and PAX3 is regulated by the overlying ectoderm, and DACH2 and PAX3 positively regulate each other's expression. Probably binds to DNA via its DACHbox-N domain. [The UniProt Consortium]

Keywords:	Anti-DACH2, Anti-Dach2, Anti-Dachshund homolog 2
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG64479

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	mouse (Expected: human)
Immunogen:	C-TRKQAVNSSRPGR
Format:	Ammonium Sulfate Precipitated