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Discount Promotion
Promotion:
Get 15% Discount on Antibodies and Biosimilars by Abeomics!
*1
*1 Offer expires 30/06/2024
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Discount | Price |
---|---|---|---|---|---|---|---|---|
ABE-10-1050-100 | 100 µg | - |
3 - 11 business days* |
15 %
|
418.00€
355.30€ |
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Cytochrome C is an inner mitochondrial membrane hemeprotein encoded by CYCS gene. Cytochrome C... more
Product information "Anti-Cytochrome C (Clone: ABM30B3)"
Cytochrome C is an inner mitochondrial membrane hemeprotein encoded by CYCS gene. Cytochrome C has two major roles within the cell, firstly, it acts as an electron carrier between Complex III (Cytochrome bc1 complex) and Complex IV (Cytochrome C oxidase). The second important function of Cytochrome C is in apoptosis. In response to extrinsic or intrinsic signals and upon suppression of anti-apoptotic molecules, several pro-apoptotic molecules are activated that disturb the mitochondrial membrane permeability and causes the release of Cytochrome C. Cytochrome C then binds to apoptotic protease activating factor-1 (Apaf-1). This complex interacts with pro-caspase 9 and initiates the caspase cascade resulting in apoptosis. Human Cytochrome C has a molecular mass of 11 kDa. Defect in the CYCS gene is associated with autosomal dominant diseases like thrombocytopenia type 4 (THC4). High levels of Cytochrome C are found in blood leukocytes, kidney, liver, heart and brain. Protein function: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. [The UniProt Consortium]
Keywords: | Anti-CYC, Anti-CYCS, Anti-Cytochrome c, Monoclonal antibody to Cytochrome C (Clone: ABM30B3) |
Supplier: | Abeomics |
Supplier-Nr: | 10-1050 |
Properties
Application: | FC, WB |
Antibody Type: | Monoclonal |
Clone: | ABM30B3 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | rat, mouse, human |
Immunogen: | Full length recombinant Cytochrome C protein was used as the immunogen for this antibody. |
Format: | Purified |
Database Information
KEGG ID : | K08738 | Matching products |
UniProt ID : | P99999 | Matching products |
Gene ID | GeneID 54205 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
-15 %
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