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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG41248.100 | 100 µl | - | - |
6 - 14 business days* |
624.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: PPIase that catalyzes the cis-trans isomerization of proline imidic peptide... more
Product information "Anti-Cyclophilin F"
Protein function: PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (PubMed:20676357). Involved in regulation of the mitochondrial permeability transition pore (mPTP). It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probability of the mPTP leading to apoptosis or necrosis, the requirement of the PPIase activity for this function is debated. In cooperation with mitochondrial TP53 is involved in activating oxidative stress-induced necrosis. Involved in modulation of mitochondrial membrane F(1)F(0) ATP synthase activity and regulation of mitochondrial matrix adenine nucleotide levels. Has anti-apoptotic activity independently of mPTP and in cooperation with BCL2 inhibits cytochrome c-dependent apoptosis. [The UniProt Consortium]
Keywords: | Anti-CypD, Anti-PPIF, Anti-CYP3, Anti-CyP-M, Anti-CyP-D, Anti-PPIase F, Anti-Rotamase F, Anti-Cyclophilin F, Anti-Cyclophilin D, Anti-Mitochondrial cyclophilin, Anti-Peptidyl-prolyl cis-trans isomerase F, mitochondrial |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG41248 |
Properties
Application: | IHC (paraffin), WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Synthetic peptide derived from Human Cyclophilin F |
MW: | 17 kD |
Format: | Affinity Purified |
Database Information
KEGG ID : | K09565 | Matching products |
UniProt ID : | P30405 | Matching products |
Gene ID | GeneID 10105 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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