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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
C8376-25A.100 | 100 tests | - | - |
3 - 19 business days* |
978.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The G protein-coupled receptor RDC-1 belongs to a subgroup of chemokine receptors and has been... more
Product information "Anti-CXCR7 (G-protein Coupled Receptor 159, Chemokine Orphan Receptor 1, G-protein Coupled Receptor"
The G protein-coupled receptor RDC-1 belongs to a subgroup of chemokine receptors and has been designated CXCR7. CXCR7 can bind with high-affinity to CXCL12/SDF-1 and CXCL11/I-TAC. It is also a co-receptor for several HIV and SIV strains. In their N-termini and extracellular loops 1, 2, and 3, human and mouse CXCR7 share 84%, 100%, 96% and 86% aa sequence identity, respectively. Reports of mRNA levels and/or protein expression (as assessed using anti-CXCR7, clone 9C4) indicate that CXCR7 occurs on a wide variety of tissues and cells including monocytes, B cells, T cells and mature dendritic cells. In contrast, based on ligand binding and receptor level analyses (as assessed using C8376-25A), surface expression of CXCR7 was reported to be restricted primarily to tumor cells, activated endothelial cells, and fetal liver cells. The basis of these inconsistent observations is not known but may be attributed to cell context and the use of different antibodies that may recognize different epitopes. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 10ul labels 1-2.5x10e5 cells. , Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C. Stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing Allophycocyanin conjugates will result in a substantial loss of eactivity. APC is light sensitive.
Keywords: | Anti-Chemokine orphan receptor 1, Anti-G-protein coupled receptor 159, Anti-C-X-C chemokine receptor type 7, Anti-G-protein coupled receptor RDC1 homolog |
Supplier: | United States Biological |
Supplier-Nr: | C8376-25A |
Properties
Application: | FC |
Antibody Type: | Monoclonal |
Clone: | 11C11 |
Conjugate: | APC |
Host: | Mouse |
Species reactivity: | human, mouse |
Immunogen: | Plasmid encoding human CXCR7/RDC-1 (hCXCR7/RDC-1, Accession # P25106). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K04304 | Matching products |
UniProt ID : | P25106 | Matching products |
Gene ID | GeneID 57007 | Matching products |
Handling & Safety
Storage: | +4°C (do not freeze) |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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