Anti-CXCL12/SDF1

Item number	Size	Manual	Delivery time	Price
E-AB-40578.20	20 µl	-	7 - 16 business days*	64.00€
E-AB-40578.50	50 µl	-	7 - 16 business days*	124.00€
E-AB-40578.100	100 µl	-	7 - 16 business days*	228.00€
E-AB-40578.200	200 µl	-	7 - 16 business days*	376.00€

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The stromal cell derived factor 1 (SDF1/CXCL12) is a small, pro-inflammatory chemoattractant... more

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Product information "Anti-CXCL12/SDF1"

The stromal cell derived factor 1 (SDF1/CXCL12) is a small, pro-inflammatory chemoattractant cytokine that regulates leukocyte trafficking through interactions with its cognate 7-transmembrane G protein-coupled receptors. The SDF1/CXCL12 receptor, CXCR4, also serves as a coreceptor for the entry of human immunodeficiency virus into target cells. SDF1/CXCL12 may regulate homing and maintenance of CXCR4-expressing stem or progenitor cells, including embryonic and many somatic stem cells. Many cancer cells express CXCR4, suggesting that SDF1/CXCL12 plays a role in cancer metastasis. Alternative splicing and differential processing during maturation produce a pair of SDF1/CXCL12 isoforms (SDF1/CXCL12alpha and SDF1/CXCL12beta) that have different properties and biological activities. Additional isoforms of SDF1/CXCL12 have been reported.

Keywords:	C-X-C motif chemokine 12, Stromal cell-derived factor 1, CXCL12/SDF1 Polyclonal Antibody
Supplier:	Elabscience
Supplier-Nr:	E-AB-40578

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant Rat CXCL12 protein expressed by E.coli.