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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related... more
Product information "Anti-CXCL11"
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found f Protein function: Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses. [The UniProt Consortium]
Keywords: | Anti-IP-9, Anti-H174, Anti-ITAC, Anti-I-TAC, Anti-CXCL11, Anti-Beta-R1, Anti-C-X-C motif chemokine 11, Anti-Small-inducible cytokine B11, Anti-Interferon gamma-inducible protein 9, Anti-Interferon-inducible T-cell alpha chemoattractant, CXCL11 Polyclonal |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-61830 |
Properties
Application: | IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Recombinant protein of human CXCL11 |
Database Information
KEGG ID : | K12672 | Matching products |
UniProt ID : | O14625 | Matching products |
Gene ID | GeneID 6373 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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