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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-RQ5483 | 100 µl | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. The CTLA4 gene is a... more
Product information "Anti-CTLA-4 / CD152, clone ADCD-3"
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. The CTLA4 gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [RefSeq] Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [The UniProt Consortium]
Keywords: | Anti-CD152, Anti-CTLA4, Anti-CTLA-4, Anti-Cytotoxic T-lymphocyte protein 4, Anti-Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4 Antibody / CD152 |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | RQ5483 |
Properties
Application: | WB |
Antibody Type: | Monoclonal |
Clone: | ADCD-3 |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | A synthetic peptide specific to human CD152 / CTLA4 |
Format: | Purified |
Database Information
KEGG ID : | K06538 | Matching products |
UniProt ID : | P16410 | Matching products |
Gene ID | GeneID 1493 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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