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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES2069.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES2069.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CTD small phosphatase 1(CTDSP1) Homo sapiens This gene encodes a member of the small C-terminal... more
Product information "Anti-CTDSP1"
CTD small phosphatase 1(CTDSP1) Homo sapiens This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011], Protein function: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.. Cellular localization: Nucleus . Colocalizes with RNA polymerase II.
Keywords: | Anti-NIF3, Anti-SCP1, Anti-CTDSP1, Anti-NLI-IF, Anti-Small CTD phosphatase 1, Anti-NLI-interacting factor 3, Anti-Small C-terminal domain phosphatase 1, Anti-Nuclear LIM interactor-interacting factor 3, CTDSP1 rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES2069 |
Properties
Application: | WB, IHC, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | The antiserum was produced against synthesized peptide derived from human CTDSP1. AA range:1-50 |
MW: | 30 kD |
Format: | Antiserum |
Database Information
KEGG ID : | K15731 | Matching products |
UniProt ID : | Q9GZU7 | Matching products |
Gene ID | GeneID 58190 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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