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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ELK-ES9242.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
| ELK-ES9242.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase... more
Product information "Anti-CRADD"
This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with mental retardation. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016], Protein function: Adapter protein that associates with PIDD1 and the caspase CASP2 to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis (PubMed:9044836, PubMed:15073321, PubMed:16652156, PubMed:17159900, PubMed:17289572). Also recruits CASP2 to the TNFR-1 signaling complex through its interaction with RIPK1 and TRADD and may play a role in the tumor necrosis factor-mediated signaling pathway (PubMed:8985253). [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Cytoplasm . Nucleus .
| Keywords: | Anti-RAIDD, Anti-CRADD, Anti-Death domain-containing protein CRADD, Anti-Caspase and RIP adapter with death domain, Anti-RIP-associated protein with a death domain, CRADD rabbit pAb |
| Supplier: | ELK Biotechnology |
| Supplier-Nr: | ES9242 |
Properties
| Application: | WB, ELISA |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, rat, mouse, |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 30-110 |
| MW: | 21 kD |
| Format: | Purified |
Database Information
| KEGG ID : | K02832 | Matching products |
| UniProt ID : | P78560 | Matching products |
| Gene ID | GeneID 8738 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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