Anti-CRABP II (Cellular retinoic acid binding protein II) (Clone 3B)

The vitamin A metabolite retinoic acid (RA) regulates gene transcription by activating several members of the nuclear receptor family of ligand-activated transcription factors: the classical RA receptors RARalpha, RARbeta, and RARgamma and the peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta). The partitioning of the hormone between its receptors is regulated by two intracellular lipid-binding proteins, cellular retinoic acid-binding protein type II (CRABP-II), which delivers RA to RAR, and fatty acid-binding protein type 5 (FABP5), which shuttles it to PPARbeta/delta. [Bertin Catalog No. G01003]Clone Designation: 3B3. Formulation: (Request formulation change), Liquid Ascite. Host: Mouse. Isotype: IgG2a, ?. Applications: ELISA, ICC, IHC, WB. Cross Reactivity: (+) Mouse CRABP II, (+) Human CRABP II, (-) CRABP I.