Anti-Cortisol-3, clone 8.F.57B

Cortisol is a corticosteroid hormone produced by the adrenal cortex that is involved in the response to stress, it increases blood pressure, blood sugar levels, may cause infertility in women, and suppresses the immune system. Synthetic cortisol, also known as hydrocortisone, is used as a drug mainly to fight allergies and inflammation. Cortisol is synthesized from pregnenolone. The conversion involves hydroxylation of C-11, C-17, and C-21, the oxidation of C-3, and the isomerization of the C-5 double bond to C-4. The synthesis takes place in the zona fasciculata of the cortex of the adrenal glands. , Applications:, Suitable for use in ELISA and RIA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Affinity Constant: 1.7x10e9 L/mole, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.