Anti-CNOT3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA006408.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Component of the CCR4-NOT complex which is one of the major cellular mRNA... more

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Product information "Anti-CNOT3"

Protein function: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation, may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation, the repressive function may involve histone deacetylases. Involved in the maintenance of embryonic stem (ES) cell identity. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 83% and to rat: 83%

Keywords:	Anti-KIAA0691, Anti-CCR4-associated factor 3, Anti-Leukocyte receptor cluster member 2, Anti-CCR4-NOT transcription complex subunit 3
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA006408

Properties

Application:	ICC, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: TPAPYAQAVA PPAPSGPSTT QPRPPSVQPS GGGGGGSGGG GSSSSSNSSA GGGAGKQNGA TSYSSVVADS PAEVALSSSG GNNASSQALG PPSGPHNPPP STSKEPSA (ATA-APrEST70863)