Anti-CMBL

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ELK-ES17367.50	50 µl		-	-	Request delivery time estimate		169.00€
ELK-ES17367.100	100 µl		-	-	Request delivery time estimate		283.00€

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CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly... more

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Product information "Anti-CMBL"

CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010], Protein function: Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization: Cytoplasm, cytosol .

Keywords:	Anti-CMBL, EC=3.1.-.-, Anti-Carboxymethylenebutenolidase homolog, CMBL rabbit pAb
Supplier:	ELK Biotechnology
Supplier-Nr:	ES17367

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthesized peptide derived from human CMBL AA range: 136-186
Format:	Purified

Database Information

KEGG ID :	K01061 \| Matching products
UniProt ID :	Q96DG6 \| Matching products
Gene ID	GeneID 134147 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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