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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
034008-HRP.200 | 200 µl | - | - |
3 - 19 business days* |
993.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA... more
Product information "Anti-CLP1, CT (CLP1, HEAB, Polyribonucleotide 5'-hydroxyl-kinase Clp1, Polynucleotide kinase Clp1, P"
Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing, this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: | Anti-HEAB, Anti-CLP1, EC=2.7.1.78, Anti-Polynucleotide kinase Clp1, Anti-Polyadenylation factor Clp1, Anti-Pre-mRNA cleavage complex II protein Clp1, Anti-Polyribonucleotide 5'-hydroxyl-kinase Clp1 |
Supplier: | United States Biological |
Supplier-Nr: | 034008-HRP |
Properties
Application: | ELISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | HRP |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | CLP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-336 amino acids from the C-terminal region of human CLP1. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K14399 | Matching products |
UniProt ID : | Q92989 | Matching products |
Gene ID | GeneID 10978 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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