Anti-CHTOP

Anti-CHTOP
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-PACO47254.50 50 µg -

9 - 20 business days*

363.00€
 
CHTOP Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human, Mouse... more
Product information "Anti-CHTOP"
CHTOP Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human, Mouse and for use in ELISA, WB, IHC applications. CHTOP Antibody is a high quality polyclonal antibody for research use only.. Protein function: Plays an important role in the ligand-dependent activation of estrogen receptor target genes (PubMed:19858291). May play a role in the silencing of fetal globin genes (PubMed:20688955). Recruits the 5FMC complex to ZNF148, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. Plays an important role in the tumorigenicity of glioblastoma cells. Binds to 5-hydroxymethylcytosine (5hmC) and associates with the methylosome complex containing PRMT1, PRMT5, MEP50 and ERH. The CHTOP- methylosome complex associated with 5hmC is recruited to selective sites on the chromosome, where it methylates H4R3 and activates the transcription of genes involved in glioblastomagenesis (PubMed:25284789). [The UniProt Consortium]
Keywords: Anti-SRAG, Anti-CHTOP, Anti-HT031, Anti-C1orf77, Anti-Friend of PRMT1 protein, Anti-Chromatin target of PRMT1 protein, Anti-Small arginine- and glycine-rich protein
Supplier: Assay Genie
Supplier-Nr: PACO47254

Properties

Application: ELISA, WB, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Recombinant Human Chromatin target of PRMT1 protein (179-248AA)

Database Information

UniProt ID : Q9Y3Y2 | Matching products
Gene ID GeneID 26097 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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