Anti-Chorionic Gonadotropin, human, beta7 (hCGb7), clone 3H479

Human Chorionic Gonadotropin (HCG) is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the a-and b-subunits. The a-subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP), and HCG but negative for EMA and AFP is probably a choriocarcinoma. Applications: Suitable for use in RIA, ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: non-reducing conditions, Optimal dilutions to be determined by the researcher. Recommended Secondary Antibodies: I1904-04D IgG, H&L (AP) Pab Gt xMo, I1904-06D IgG, H&L, X-Adsorbed (AP) Pab Gt xMo, I1904-04A: IgG, H&L (FITC) Pab Gt xMo, I1904-06F: IgG, H&L (FITC) (X-Adsorbed) Pab Gt xMo, I1904-06C: IgG, H&L (HRP) (X-Adsorbed) Pab Gt xMo, I1904-06H IgG, H&L (HRP) (X-Adsorbed) Pab Gt xMo, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.