Anti-CENPA

Anti-CENPA
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-CAB15995.50 50 µl - -

9 - 20 business days*

352.00€
G-CAB15995.100 100 µl -

9 - 20 business days*

448.00€
 
WB 1:500 - 1:2000. Protein function: Histone H3-like nucleosomal protein that is specifically... more
Product information "Anti-CENPA"
WB 1:500 - 1:2000. Protein function: Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes (PubMed:7962047, PubMed:9024683, PubMed:11756469, PubMed:14667408, PubMed:15702419, PubMed:15475964, PubMed:15282608, PubMed:17651496, PubMed:19114591, PubMed:27499292, PubMed:20739937). Replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore (PubMed:18072184). The presence of CENPA subtly modifies the nucleosome structure and the way DNA is wrapped around the nucleosome and gives rise to protruding DNA ends that are less well-ordered and rigid compared to nucleosomes containing histone H3 (PubMed:27499292, PubMed:26878239). May serve as an epigenetic mark that propagates centromere identity through replication and cell division (PubMed:15475964, PubMed:15282608, PubMed:26878239, PubMed:20739937, PubMed:21478274). Required for recruitment and assembly of kinetochore proteins, and as a consequence required for progress through mitosis, chromosome segregation and cytokinesis (PubMed:11756469, PubMed:14667408, PubMed:18072184, PubMed:23818633, PubMed:25556658, PubMed:27499292). [The UniProt Consortium]
Keywords: Anti-CENPA, Anti-CENP-A, Anti-Centromere protein A, Anti-Centromere autoantigen A, Anti-Histone H3-like centromeric protein A, CENPA Polyclonal Antibody (CAB15995)
Supplier: Assay Genie
Supplier-Nr: CAB15995

Properties

Application: WB, IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-CENPA"
Write a review
or to review a product.
Viewed