Anti-CDw75 (B-Cell Marker) Monoclonal Antibody (Clone: ZB55)

Recognizes a neuraminidase-sensitive sialoprotein (CDw75), present on cell membrane and cytoplasm of germinal center B-cells and derived lymphomas. This MAb reacts with RBC precursors of bone marrow, ductal and ciliated epithelial cells of kidney, breast, prostate, pancreas, lung, and with glioblastomas, astrocytomas, and Reed Sternberg cells in lymphocyte predominant Hodgkin s disease. It is shown to be a helpful antibody for ascribing a B-cell phenotype in known lymphoid tissues. Protein function: Transfers sialic acid from CMP-sialic acid to galactose- containing acceptor substrates. [The UniProt Consortium]