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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| A300-786A-T | 10 µl (1000 µg/ml) | - |
2 - 8 business days* |
164.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CDT1 is involved in the formation of pre-replicative complexes (preRC) at origins of replication.... more
Product information "Anti-CDT1"
CDT1 is involved in the formation of pre-replicative complexes (preRC) at origins of replication. Under tight regulation, CDT1 associates with chromatin during G1 in a dynamic manner to promote the loading of mini-chromosome maintenance (MCM) complex in preparation for replication. CDT1 is negatively regulated by ubiquitin-directed degradation and has been demonstrated to be protected from ubiquitination by the protein geminin. Protein function: Required for both DNA replication and mitosis (PubMed:11125146, PubMed:22581055, PubMed:21856198, PubMed:14993212, PubMed:26842564). DNA replication licensing factor, required for pre- replication complex assembly. Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to generate pre-replication complexes (pre-RC)(PubMed:14672932). Required also for mitosis by promoting stable kinetochore-microtubule attachments (PubMed:22581055). Potential oncogene. [The UniProt Consortium]
| Keywords: | Anti-DUP, Anti-Double parked homolog, Anti-DNA replication factor Cdt1 |
| Supplier: | Bethyl Laboratories |
| Supplier-Nr: | A300-786A |
Properties
| Application: | WB, IP, IHC |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Format: | Antigen Affinity Purified |
Database Information
| KEGG ID : | K10727 | Matching products |
| UniProt ID : | Q9H211 | Matching products |
| Gene ID | GeneID 81620 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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