Anti-CDKN3

Anti-CDKN3
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES4465.50 50 µl - -

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169.00€
ELK-ES4465.100 100 µl - -

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283.00€
 
The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It... more
Product information "Anti-CDKN3"
The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008], Protein function: May play a role in cell cycle regulation. Dual specificity CC phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues (PubMed:8127873, PubMed:8242750). Dephosphorylates CDK2 at 'Thr-160' in a cyclin-dependent manner (PubMed:7569954). [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.. Cellular localization: Cytoplasm, perinuclear region .
Keywords: Anti-CDI1, Anti-Kinase-associated phosphatase, Anti-Cyclin-dependent kinase inhibitor 3, Anti-Cyclin-dependent kinase interactor 1, Anti-CDK2-associated dual-specificity phosphatase, Anti-Cyclin-dependent kinase-interacting protein 2, CDKN3 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES4465

Properties

Application: WB, IHC, IF, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: The antiserum was produced against synthesized peptide derived from human CDKN3. AA range:31-80
MW: 23 kD
Format: Antiserum

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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