Anti-CDKN1B

Anti-CDKN1B
Item number Size Datasheet Manual SDS Delivery time Quantity Price
030083.100 100 µl - -

3 - 19 business days*

477.00€
 
p27 KIP 1 is a cell cycle regulatory mitotic inhibitor of cdk activity. p27 KIP 1 is a candidate... more
Product information "Anti-CDKN1B"
p27 KIP 1 is a cell cycle regulatory mitotic inhibitor of cdk activity. p27 KIP 1 is a candidate tumor suppressor gene, and has been proposed to function as a possible mediator of TGF beta induced G1 arrest. p27 KIP 1 is up regulated in response to antimitogenic stimuli. The increased protein expression of p27 results in cellular arrest by binding to cyclin/Cdk complexes such as cyclin D1/Cdk4. Decreased levels of p27Kip1, mainly due to proteosomal degradation, are found in various epithelial tumors originating from lung, breast, colon, ovary, esophagus, thyroid and prostate.Tissue specificity: Expressed in all tissues tested. Highest levels in skeletal muscle, lowest in liver and kidney. Applications: Western Bloting: 1:500-1:2000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-KIP1, Anti-CDKN1B, Anti-p27Kip1, Anti-Cyclin-dependent kinase inhibitor 1B, Anti-Cyclin-dependent kinase inhibitor p27
Supplier: United States Biological
Supplier-Nr: 030083

Properties

Application: ELISA, WB
Antibody Type: Monoclonal
Clone: 13B161
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Purified recombinant fragment of human CDKN1B expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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