Anti-CDC42BPB (PACO01083)

Anti-CDC42BPB (PACO01083)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-PACO01083.50 50 µg - -

9 - 20 business days*

320.00€
 
CDC42BPB Antibody from Assay Genie with reactivity against Human, Mouse, Rat and for use in... more
Product information "Anti-CDC42BPB (PACO01083)"
CDC42BPB Antibody from Assay Genie with reactivity against Human, Mouse, Rat and for use in ELISA, WB, IHC applications. CDC42BPB Antibody is Polyclonal and is a IgG isotype antibody from Assay Genie.. Protein function: Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2 (PubMed:21457715, PubMed:21949762). In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). Phosphorylates PPP1R12A (PubMed:21457715). In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation. [The UniProt Consortium]
Keywords: Anti-MRCK beta, EC=2.7.11.1, Anti-CDC42BP-beta, Anti-DMPK-like beta, Anti-CDC42-binding protein kinase beta, Anti-Serine/threonine-protein kinase MRCK beta, Anti-Myotonic dystrophy protein kinase-like beta
Supplier: Assay Genie
Supplier-Nr: PACO01083

Properties

Application: ELISA, WB, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: synthesized peptide derived from the C-terminal region of human MRCKBeta.
Formula: affinity purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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