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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-30-1923-100 | 100 tests | - |
3 - 11 business days* |
653.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CD89 (Fc-alpha-R) is a type I transmembrane glycoprotein serving as a receptor for IgA. Soluble... more
Product information "Anti-CD89 Monoclonal Antibody (Clone:A59)-FITC Conjugated"
CD89 (Fc-alpha-R) is a type I transmembrane glycoprotein serving as a receptor for IgA. Soluble CD89 is detectable in serum and retains its IgA binding capacity. For signal transduction the association with FcR gamma chain homodimers is needed. CD89 is expressed on granulocytes, monocytes, macrophages, dendritic cells and myeloid cell lines. Its expression is upregulated in presence of IgA immune complexes, stimulators (such as LPS, PMA), TNF alpha, IL1 beta or GM-CSF, and it is downregulated in presence of TGF beta and suramin. Binding of IgA-opsonized targets to CD89 leads to phagocytic and cytotoxic processes of the immunologic defense. Protein function: Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. [The UniProt Consortium]
Keywords: | Anti-CD89, Anti-FCAR, Anti-IgA Fc receptor, Anti-Immunoglobulin alpha Fc receptor, Anti-CD89 Monoclonal Antibody (Clone:A59)-FITC Conjugated |
Supplier: | Abeomics |
Supplier-Nr: | 30-1923 |
Properties
Application: | FC |
Antibody Type: | Monoclonal |
Clone: | A59 |
Conjugate: | FITC |
Host: | Mouse |
Species reactivity: | human, non-human primates |
Immunogen: | Ag8.653 myeloma cells |
Database Information
KEGG ID : | K06513 | Matching products |
UniProt ID : | P24071 | Matching products |
Gene ID | GeneID 2204 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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