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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-30-1481-0.1 | 100 µg | - |
3 - 11 business days* |
594.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CD83 is a 40-45 kDa heavily glycosylated type I cell surface glycoprotein of immunoglobulin... more
Product information "Anti-CD83 Monoclonal Antibody (Clone:HB15e)"
CD83 is a 40-45 kDa heavily glycosylated type I cell surface glycoprotein of immunoglobulin family. It is expressed on the surface of mature dendritic cells, Langerhans cells in the skin, and interdigitating reticulum cells in the lymphoid tissues. Low expression of CD83 has been reported in activated T and B cells. Cytoplasmic expression of CD83 can be detected also in monocytes and macrophages. CD83 is involved in modulation of antigen presentation. Soluble CD83 has immunoregulatory functions, it is able to down-regulate dendritic cell maturation and stimulation of T cells. In the developing immune system, release of soluble CD83 from dendritic cells upon stimulation by gram-positive or gram-negative bacteria has anti-allergic effect. Herpes simplex virus, on the other hand, causes CD83 degradation in mature dendritic cells. Protein function: May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation. [The UniProt Consortium]
Keywords: | Anti-CD83, Anti-hCD83, Anti-CD83 antigen, Anti-Cell surface protein HB15, Anti-B-cell activation protein, Anti-CD83 Monoclonal Antibody (Clone:HB15e) |
Supplier: | Abeomics |
Supplier-Nr: | 30-1481 |
Properties
Application: | FC, IHC (frozen) |
Antibody Type: | Monoclonal |
Clone: | HB15e |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, non-human primates |
Immunogen: | Human CD83-transfected Cos cells |
Format: | Affinity Purified |
Database Information
KEGG ID : | K06510 | Matching products |
UniProt ID : | Q01151 | Matching products |
Gene ID | GeneID 9308 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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