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Discount Promotion
Promotion:
Get 15% Discount on Antibodies and Biosimilars by Abeomics!
*1
*1 Offer expires 30/06/2024
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Discount | Price |
---|---|---|---|---|---|---|---|---|
ABE-10-7504-F-100 | 100 µg | - |
3 - 11 business days* |
15 %
|
343.00€
291.55€ |
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CD56, a 175-220 KDa glycoprotein, is a member of the Ig super family. It is expressed as three... more
Product information "Anti-CD56-FITC conjugated (Clone: 123C3)"
CD56, a 175-220 KDa glycoprotein, is a member of the Ig super family. It is expressed as three major isoforms and consists of five Ig-like domains and two Fibronectin-type III domains in the extracellular region. The 135 kDa isoform is the basic molecule which is glycosylated or sialylated to produce the mature species. CD56 is widely expressed in nervous system, on NK cells and a specific set of Tcells. CD56+ NK cells and Tcells are unique in their ability to mediate cell-mediated cytotoxicity against certain tumor cell targets without MHC restriction. Other physiological functions of CD56 include mediating cell adhesion through homophilic and heterophilic interaction and activating intracellular signaling pathways resulting in neutrite extension and fasciculation, migration and synapses formation in brain. CD56 is also vital for neuronal development and plasticity in adult brain. It is used as a tumor marker in various cancers such as NK lymphomas and Merkel cell carcinoma. NCAM is expressed on most neuroectodermal derived lines, tissues, and neoplasms such as retinoblastoma, medulloblastoma, astrocytoma, and neuroblastoma. It is also expressed on some mesodermally derived tumors such as rhabdomyosarcoma and also on natural killer cells. Protein function: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. [The UniProt Consortium]
Keywords: | Anti-NCAM, Anti-CD56, Anti-NCAM1, Anti-NCAM-1, Anti-N-CAM-1, Anti-Neural cell adhesion molecule 1, Monoclonal Antibody to CD56-FITC conjugated (Clone: 123C3) |
Supplier: | Abeomics |
Supplier-Nr: | 10-7504-F |
Properties
Application: | FC |
Antibody Type: | Monoclonal |
Clone: | 123C3 |
Conjugate: | FITC |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | The immunogen for this CD56 antibody was a membrane preparation of a small cell lung carcinoma. |
Format: | Purified |
Database Information
KEGG ID : | K06491 | Matching products |
UniProt ID : | P13591 | Matching products |
Gene ID | GeneID 4684 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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