Anti-CD50 / ICAM-3(Clone: SPM505)

Anti-CD50 / ICAM-3(Clone: SPM505)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-36-1254-100 100 µg -

3 - 11 business days*

662.00€
 
Recognizes the D1 domain of an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide... more
Product information "Anti-CD50 / ICAM-3(Clone: SPM505)"
Recognizes the D1 domain of an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb is excellent for staining of formalin/paraffin tissues. Protein function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2) (PubMed:1448173). ICAM3 is also a ligand for integrin alpha-D/beta-2. In association with integrin alpha-L/beta-2, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590). [The UniProt Consortium]
Keywords: Anti-CD50, Anti-ICAM3, Anti-CDw50, Anti-ICAM-3, Anti-ICAM-R, Anti-Intercellular adhesion molecule 3, Monoclonal Antibody to CD50 / ICAM-3(Clone: SPM505)
Supplier: Abeomics
Supplier-Nr: 36-1254

Properties

Application: FC, IF, IHC
Antibody Type: Monoclonal
Clone: SPM505
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Stimulated human leukocytes
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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