Anti-CD50 / ICAM-3(Clone: SPM505)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABE-36-1254-100	100 µg		-		3 - 11 business days*		853.00€

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Recognizes the D1 domain of an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide... more

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Product information "Anti-CD50 / ICAM-3(Clone: SPM505)"

Recognizes the D1 domain of an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb is excellent for staining of formalin/paraffin tissues. Protein function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2) (PubMed:1448173). ICAM3 is also a ligand for integrin alpha-D/beta-2. In association with integrin alpha-L/beta-2, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590). [The UniProt Consortium]

Keywords:	Anti-CD50, Anti-ICAM3, Anti-CDw50, Anti-ICAM-3, Anti-ICAM-R, Anti-Intercellular adhesion molecule 3, Monoclonal Antibody to CD50 / ICAM-3(Clone: SPM505)
Supplier:	Abeomics
Supplier-Nr:	36-1254

Properties

Application:	FC, IF, IHC
Antibody Type:	Monoclonal
Clone:	SPM505
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Stimulated human leukocytes
Format:	Affinity Purified