Anti-CD50 / ICAM-3 Monoclonal Antibody (Clone:MEM-04)-Low Endotoxin

Anti-CD50 / ICAM-3 Monoclonal Antibody (Clone:MEM-04)-Low Endotoxin
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-30-1614-0.1 100 µg -

3 - 11 business days*

490.00€
 
CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by... more
Product information "Anti-CD50 / ICAM-3 Monoclonal Antibody (Clone:MEM-04)-Low Endotoxin"
CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages, this process is involved in dialogue between dendritic cells and granulocytes. Protein function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2) (PubMed:1448173). ICAM3 is also a ligand for integrin alpha-D/beta-2. In association with integrin alpha-L/beta-2, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590). [The UniProt Consortium]
Keywords: Anti-CD50, Anti-ICAM3, Anti-CDw50, Anti-ICAM-3, Anti-ICAM-R, Anti-Intercellular adhesion molecule 3, Anti-CD50 / ICAM-3 Monoclonal Antibody (Clone:MEM-04)-Low Endotoxin
Supplier: Abeomics
Supplier-Nr: 30-1614

Properties

Application: FC, IHC, FA
Antibody Type: Monoclonal
Clone: MEM-04
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Leukocytes of a patient suffering from LGL-type leukemia.
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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