Anti-CD47 Cocktail (IAP), clone IAP/964 + B6H12.2

Anti-CD47 Cocktail (IAP), clone IAP/964 + B6H12.2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3015SAF-100UG 100 µg - -

3 - 10 business days

541.00€
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. This antibody reacts with Ig domain of CD47... more
Product information "Anti-CD47 Cocktail (IAP), clone IAP/964 + B6H12.2"
1 mg/ml in sterile PBS, BSA free, sodium azide free. This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. Protein function: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. [The UniProt Consortium]
Keywords: Anti-IAP, Anti-MER6, Anti-CD47, Anti-Protein MER6, Anti-Integrin-associated protein, Anti-Leukocyte surface antigen CD47, Anti-Antigenic surface determinant protein OA3, CD47 Antibody Cocktail (IAP)
Supplier: NSJ Bioreagents
Supplier-Nr: V3015SAF-100UG

Properties

Application: FA (activity), FC, IF, IHC (paraffin)
Antibody Type: Mixed
Clone: IAP/964+B6H12.2
Conjugate: No
Host: Mouse
Reactivity: Human, Mouse
Immunogen: Recombinant human IAP protein (IAP/964), Intact CD47 purified from placenta (B6H12.2)
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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