Anti-CD46

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG40482.50	50 µg		-	-	6 - 14 business days*		520.00€

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Protein function: Acts as a cofactor for complement factor I, a serine protease which protects... more

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Product information "Anti-CD46"

Protein function: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement- mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T- cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. [The UniProt Consortium]

Keywords:	Anti-TLX, Anti-MCP, Anti-CD46, Anti-Membrane cofactor protein, Anti-Trophoblast leukocyte common antigen
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG40482

Properties

Application:	FC, IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Synthetic peptide corresponding to aa. 366-392 of Human CD46. (YRYLQRRKKKGTYLTDETHREVKFTSL)
Format:	Antigen Affinity Purified