Anti-CD45 (protein tyrosine phosphatase, receptor type, C, B220, CD45, CD45R, GP180, LCA, L-CA, Leuk

Anti-CD45 (protein tyrosine phosphatase, receptor type, C, B220, CD45, CD45R, GP180, LCA, L-CA, Leuk
Item number Size Datasheet Manual SDS Delivery time Quantity Price
C2400-10B.100 100 µg - -

3 - 19 business days*

599.00€
 
CD45 is a receptor-tyrosine phosphatase required for antigen-induced signaling in T-cells and... more
Product information "Anti-CD45 (protein tyrosine phosphatase, receptor type, C, B220, CD45, CD45R, GP180, LCA, L-CA, Leuk"
CD45 is a receptor-tyrosine phosphatase required for antigen-induced signaling in T-cells and B-cells, its substrates are unknown. Interestingly, it associates with several Src-family tyrosine kinases, which are inhibited by tyrosine phosphorylation in their c-termini, suggesting a mechanism for signaling by CD45. The LCA comprises of at least 5 isoforms ranging from 180-220kD which are produced as a result of alternative splicing of exons A, B or C. CBL 124 recognizes epitopes common to all of the isoforms. , Antigen distribution: , Thymocytes > 95% , Granulocytes > 95% , Monocytes > 95% , B cells (CD20+) > 95% , T cells (CD3+) > 95% , NK cells (CD16+) > 95% , Peripheral blood lymphocytes > 95% , Applications: Suitable for use in Immunofluorescence, Western Blot, Immunoprecipitation, Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:500 detected CD45 on 10ug of Jurkat lysates, Optimal dilutions to be determined by the researcher. Hybridoma: NS1 myeloma cells with spleen cells from Balb/c mice. Positive Control: Jurkat cell lysate, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-PTPRC, EC=3.1.3.48, Anti-Leukocyte common antigen, Anti-Receptor-type tyrosine-protein phosphatase C
Supplier: United States Biological
Supplier-Nr: C2400-10B

Properties

Application: FC, IF, IHC, IP, WB
Antibody Type: Monoclonal
Clone: 9H217
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Purified T cells from human lymph nodes. Cellular Localization: Membrane, Single-pass type I membrane protein.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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