Anti-CD4 (soluble receptor) (T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4 precur

Anti-CD4 (soluble receptor) (T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4 precur
Item number Size Datasheet Manual SDS Delivery time Quantity Price
C2255-82A.200 200 µg - -

3 - 19 business days*

552.00€
 
CD4, a single chain transmembrane glycoprotein is found on a T cell subset (helper/inducer)... more
Product information "Anti-CD4 (soluble receptor) (T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4 precur"
CD4, a single chain transmembrane glycoprotein is found on a T cell subset (helper/inducer) representing 45% of peripheral blood lympocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV. Antibody to CD4 recognizes T-helper cells required for recognition of class II antigens. It reacts with 60% of peripheral blood E rosette-positive (E+) cells while showing negligible reactivity with E+ cells, monocytes, granulocytes, EBV-transformed B cell lines, and mouse splenocytes. CD4-positive T-cells provide helper funciton in pokeweed mitogen driven B-cell differentiation. Moreover, anti-CD4 selectively blocks the autologus mixed lymphocyte reaction (AMLR) with minimal or no effect on the allogeneic MLR (allo-MLR). Blocking of the autoreactivity occurs when either autologus B-lymphocytes or macrophages are used as stimulators. Specificity closely approximates the binding spectrum of OKT4 and Leu-3 antibodies both of which also recognize 55 to 65% of human peripheral blood T-cells. , Applications: , Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: United States Biological
Supplier-Nr: C2255-82A

Properties

Application: ELISA
Antibody Type: Monoclonal
Clone: 9F602
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Human recombinant CD-4 expressed in CHO cells
Format: Affinity Purified

Database Information

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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