Anti-CD38 Monoclonal Antibody (Clone:HIT2)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABE-30-1242-0.1	100 µg		-		3 - 11 business days*		594.00€

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CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation,... more

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Product information "Anti-CD38 Monoclonal Antibody (Clone:HIT2)"

CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. Another role of CD38 is provided by enzymatic activity of its extracellular part. CD38 acts as NAD+ glycohydrolase converting NAD+ into ADP-ribose, as ADP-ribosyl cyclase producing cADPR and as cADPR hydrolase, thus affecting levels of calcium-mobilizing metabolites. ADPR produced by CD38 serves as an important second messenger of neutrophil and dendritic cell migration. Protein function: Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. [The UniProt Consortium]

Keywords:	Anti-T10, Anti-CD38, Anti-ADPRC 1, EC=3.2.2.6, EC=2.4.99.20, Anti-cADPr hydrolase 1, Anti-ADP-ribosyl cyclase 1, Anti-Cyclic ADP-ribose hydrolase 1, Anti-2'-phospho-ADP-ribosyl cyclase, Anti-2'-phospho-cyclic-ADP-ribose transferase, Anti-CD38 Monoclonal A
Supplier:	Abeomics
Supplier-Nr:	30-1242

Properties

Application:	FC, WB, IHC, IHC (frozen)
Antibody Type:	Monoclonal
Clone:	HIT2
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Human thymocytes in foetus
Format:	Affinity Purified