Anti-CD33, clone WM53

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG65560.100	100 µg		-	-	6 - 14 business days*		608.00€

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Protein function: Putative adhesion molecule of myelomonocytic-derived cells that mediates... more

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Product information "Anti-CD33, clone WM53"

Protein function: Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro). [The UniProt Consortium]

Keywords:	Anti-gp67, Anti-CD33, Anti-SIGLEC3, Anti-Siglec-3, Anti-Myeloid cell surface antigen CD33, Anti-Sialic acid-binding Ig-like lectin 3
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG65560

Properties

Application:	FC, IP, WB, IHC (frozen), ICC, IF, FA
Antibody Type:	Monoclonal
Clone:	WM53
Conjugate:	No
Host:	Mouse
Species reactivity:	human, primates
Immunogen:	Human AML cells
Format:	Affinity Purified