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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-30-1462-0.1 | 100 µg | - |
3 - 11 business days* |
536.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CD28 is the critical T cell costimulatory receptor which provides to the cell the important... more
Product information "Anti-CD28 Monoclonal Antibody (Clone:JJ319)"
CD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. Its analog CTLA-4, expressed on the surface of activated T cells, has higher affinity to CD80 and CD86 than CD28 and downregulates T cell activity. Protein function: Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation. [The UniProt Consortium]
Keywords: | Anti-CD28, Anti-Cd28, Anti-T-cell-specific surface glycoprotein CD28, Anti-CD28 Monoclonal Antibody (Clone:JJ319) |
Supplier: | Abeomics |
Supplier-Nr: | 30-1462 |
Properties
Application: | FC, IP, FA |
Antibody Type: | Monoclonal |
Clone: | JJ319 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | rat |
Immunogen: | Mouse A20J B lymphoma cells transfected with rat CD28 |
Format: | Affinity Purified |
Database Information
KEGG ID : | K06470 | Matching products |
UniProt ID : | P31042 | Matching products |
Gene ID | GeneID 25660 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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