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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-36-2587-20 | 20 µg | - |
3 - 11 business days* |
375.00€
|
|||
ABE-36-2587-100 | 100 µg | - |
3 - 11 business days* |
853.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Recognizes a protein of 55kDa, identified as CD25. It is expressed on activated T- and B-cells... more
Product information "Anti-CD25 / IL2RA (Activated Lymphocyte Marker) Monoclonal Antibody (Clone: IL2RA/2394)"
Recognizes a protein of 55kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkin's disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25. Protein function: Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. [The UniProt Consortium]
Keywords: | Anti-p55, Anti-CD25, Anti-IL2RA, Anti-IL2-RA, Anti-IL-2-RA, Anti-TAC antigen, Anti-IL-2R subunit alpha, Anti-IL-2 receptor subunit alpha, Anti-Interleukin-2 receptor subunit alpha, Anti-CD25 / IL2RA (Activated Lymphocyte Marker) Monoclonal Antibody (Clone |
Supplier: | Abeomics |
Supplier-Nr: | 36-2587 |
Properties
Application: | ELISA |
Antibody Type: | Monoclonal |
Clone: | IL2RA/2394 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Recombinant human IL2RA protein fragment (around aa 42-183) (exact sequence is proprietary) |
Database Information
KEGG ID : | K05068 | Matching products |
UniProt ID : | P01589 | Matching products |
Gene ID | GeneID 3559 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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