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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
C2275-89E.100 | 100 µg | - | - |
3 - 19 business days* |
534.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The IL-2 receptor (IL-2R) exists in three alternative forms made up from the individual... more
Product information "Anti-CD25 (Tac antigen, p55, Interleukin 2 Receptor alpha, IL2Ra, T Cell Growth Factor Receptor), AP"
The IL-2 receptor (IL-2R) exists in three alternative forms made up from the individual components of CD25, CD122, and CD132. CD25 represents the low affinity alpha chain of the IL-2R, a type I transmembrane glycoprotein containing two CCP domains. It is rich in O-linked carbohydrates and has a short cytoplasmic tail. CD25 is expressed on activated T cells, B cells, NK cells and monocytes of all mouse strains tested. It is transiently expressed at a low level during B-cell development in bone marrow on the CD45R/B220low TdT- sIg- pre-B II and CD45R/B220low TdT- sIgM+sIgD- immature B cells, but not on the CD45R/B220low TdT+ sIg- pro-B/pre-B I stage nor on CD45R/B220high TdT- sIgM+sIgD+ mature B cells. CD25 is expressed at a higher level during very early T-cell development in fetal and adult thymus. While the antibody does not block the binding of IL-2 to CD25, when used in combination with C2275-82 it results in higher levels of inhibition of IL-2-driven proliferation than either of these two monoclonal antibodies alone. Applications: Flow cytometry 1, 3, 4, 7, 8, Immunoprecipitation 1, 3, Recommended Dilution: Flow Cytometry: < 0.2ug/10e6 cells, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: | United States Biological |
Supplier-Nr: | C2275-89E |
Properties
Application: | FC, IP |
Antibody Type: | Monoclonal |
Clone: | 5K251 |
Conjugate: | Alkaline Phosphatase |
Host: | Rat |
Species reactivity: | mouse |
Immunogen: | IL-2-dependent BALB/c mouse helper T-cell clone HT-2 |
Format: | Purified |
Database Information
Handling & Safety
Storage: | +4°C (frozen cool packs!) |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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