Anti-CD22 (FITC), clone 2D6

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG20868.100	100 µg		-	-	6 - 14 business days*		608.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Mediates B-cell B-cell interactions. May be involved in the localization of... more

Close menu

Product information "Anti-CD22 (FITC), clone 2D6"

Protein function: Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins, one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. [The UniProt Consortium]

Keywords:	Anti-CD22, Anti-Cd22, Anti-Lyb-8, Anti-BL-CAM, Anti-Siglec-2, Anti-B-cell receptor CD22, Anti-T-cell surface antigen Leu-14, Anti-B-lymphocyte cell adhesion molecule, Anti-Sialic acid-binding Ig-like lectin 2
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG20868

Properties

Application:	FC, IHC (frozen), IHC (paraffin), ICC, IF, Cell-Act
Antibody Type:	Monoclonal
Clone:	2D6
Conjugate:	FITC
Host:	Rat
Species reactivity:	mouse
Immunogen:	Splenic lymphocyte plasma membranes from CBA x C57 F1 mice