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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-30-1446-0.1 | 100 µg | - |
3 - 11 business days* |
637.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CD180, also known as RP105 (or Bgp95, LY64) is a type I membrane glycoprotein of Toll-like... more
Product information "Anti-CD180 Monoclonal Antibody (Clone:G28-8)"
CD180, also known as RP105 (or Bgp95, LY64) is a type I membrane glycoprotein of Toll-like receptor (TLR) family. Its cytoplasmic tail is short and unlike the TLRs, it lacks the TIR domain. CD180 expression is dependent on the coexpression of its helper molecule, MD-1 , and mirrors that of TLR4 on antigen-presenting cells. CD180 regulates recognition of LPS and signaling in B cells, via interacting directly with the TLR4 signaling complex, inhibiting its ability to bind microbial ligands. Ligation of CD180 by monoclonal antibodies leads to B cell activation, upregulation of CD80/CD86, and increase in cell size. Protein function: May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells. [The UniProt Consortium]
Keywords: | Anti-LY64, Anti-CD180, Anti-CD180 antigen, Anti-Lymphocyte antigen 64, Anti-Radioprotective 105 kDa protein, Anti-CD180 Monoclonal Antibody (Clone:G28-8) |
Supplier: | Abeomics |
Supplier-Nr: | 30-1446 |
Properties
Application: | FC, IP, FA |
Antibody Type: | Monoclonal |
Clone: | G28-8 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Human tonsillar B cells |
Format: | Affinity Purified |
Database Information
KEGG ID : | K06555 | Matching products |
UniProt ID : | Q99467 | Matching products |
Gene ID | GeneID 4064 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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