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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-CAB13597.50 | 50 µl | - | - |
9 - 20 business days* |
352.00€
|
||
| G-CAB13597.100 | 100 µl | - |
9 - 20 business days* |
448.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
IF 1:50 - 1:200. Protein function: In association with beta-2 integrin heterodimer ITGAM/CD11b... more
Product information "Anti-CD177"
IF 1:50 - 1:200. Protein function: In association with beta-2 integrin heterodimer ITGAM/CD11b and ITGB2/CD18, mediates activation of TNF-alpha primed neutrophils including degranulation and superoxide production (PubMed:21193407). In addition, by preventing beta-2 integrin internalization and attenuating chemokine signaling favors adhesion over migration (PubMed:28807980). Heterophilic interaction with PECAM1 on endothelial cells plays a role in neutrophil transendothelial migration in vitro (PubMed:17580308). However, appears to be dispensable for neutrophil recruitment caused by bacterial infection in vivo (PubMed:23461681). Acts as a receptor for the mature form of protease PRTN3 allowing its display at the cell surface of neutrophils (PubMed:17244676, PubMed:18462208). By displaying PRTN3 at the neutrophil cell surface, may play a role in enhancing endothelial cell junctional integrity and thus vascular integrity during neutrophil diapedesis (PubMed:23202369). [The UniProt Consortium]
| Keywords: | Anti-NB1, Anti-PRV-1, Anti-CD177, Anti-NB1 GP, Anti-HNA-2a, Anti-CD177 antigen, Anti-NB1 glycoprotein, Anti-Human neutrophil alloantigen 2a, Anti-Polycythemia rubra vera protein 1, CD177 Polyclonal Antibody (CAB13597) |
| Supplier: | Assay Genie |
| Supplier-Nr: | CAB13597 |
Properties
| Application: | IF |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
Database Information
| KEGG ID : | K06552 | Matching products |
| UniProt ID : | Q8N6Q3 | Matching products |
| Gene ID | GeneID 57126 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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