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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
C2548-88H.100 | 100 µg | - | - |
3 - 19 business days* |
552.00€
|
||
C2548-88H.250 | 250 µg | - | - |
3 - 19 business days* |
765.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after... more
Product information "Anti-CD161 (CLEC5B, Killer Cell Lectin-like Receptor Subfamily B Member 1, KLRB1, MGC138614, NKR, NK"
Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein, NKR-P1A or D161, is classified as a type II membrane protein because it has an external C terminus.[1] NKR-P1A, the receptor encoded by the KLRB1 gene, recognizes Lectin Like Transcript-1 (LLT1) as a functional ligand. Human CD161 is a homodimeric disulfide-linked type II membrane bound glycoprotein found mainly on NK cells. CD161 has been implicated in the regulation of NK cell mediated cytotoxicity. Applications: Suitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation. Other applications not tested. Recommended Dilutions: Flow Cytometry: 1:50-1:100, 10ul labels 10e6 cells in 100ul, Immunohistochemistry: Frozen sections, Optimal dilutions to be determined by the researcher. Hybridoma: X63-Ag8653 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: | United States Biological |
Supplier-Nr: | C2548-88H |
Properties
Application: | FC, IHC, IP |
Antibody Type: | Monoclonal |
Clone: | 6A381 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | rat |
Immunogen: | Purified splenic NK cells from the LEW rat strain. |
Format: | Affinity Purified |
Database Information
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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