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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-30-1822-100 | 100 tests | - |
3 - 11 business days* |
713.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CD152 / CTLA-4 is a homodimeric transmembrane protein similar to CD28 and binding the same... more
Product information "Anti-CD152 / CTLA4 Monoclonal Antibody (Clone:BNI3)-APC Conjugated"
CD152 / CTLA-4 is a homodimeric transmembrane protein similar to CD28 and binding the same ligands, i.e. CD80 (B7.1) and CD86 (B7.2), but with higher affinity. Unlike CD28 with important costimulating functions, CD152 acts as an important inhibitory receptor essential for modulation of the immune system. CD152 / CTLA-4 becomes transiently expressed on activated T cells and its malfunction can cause autoimmune diseases, such as insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, or thyroid-associated orbitopathy. Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. [The UniProt Consortium]
Keywords: | Anti-CD152, Anti-CTLA4, Anti-CTLA-4, Anti-Cytotoxic T-lymphocyte protein 4, Anti-Cytotoxic T-lymphocyte-associated antigen 4, Anti-CD152 / CTLA4 Monoclonal Antibody (Clone:BNI3)-APC Conjugated |
Supplier: | Abeomics |
Supplier-Nr: | 30-1822 |
Properties
Application: | FC, IP, IHC (frozen), ICC |
Antibody Type: | Monoclonal |
Clone: | BNI3 |
Conjugate: | APC |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Human CD152-IgG heavy chain fusion protein |
Database Information
KEGG ID : | K06538 | Matching products |
UniProt ID : | P16410 | Matching products |
Gene ID | GeneID 1493 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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