Anti-CD11b (mouse) (APC), clone M1/70.15

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
G-AGIM0551.100	100 µl		-		9 - 20 business days*		213.00€

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Protein function: Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of... more

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Product information "Anti-CD11b (mouse) (APC), clone M1/70.15"

Protein function: Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration. In association with beta subunit ITGB2/CD18, required for CD177-PRTN3-mediated activation of TNF primed neutrophils. May regulate phagocytosis-induced apoptosis in extravasated neutrophils. May play a role in mast cell development. [The UniProt Consortium]

Keywords:	Anti-CD11b, Anti-Itgam, Anti-CR-3 alpha chain, Anti-Integrin alpha-M, Anti-Leukocyte adhesion receptor MO1, Anti-CD11 antigen-like family member B, Anti-Cell surface glycoprotein MAC-1 subunit alpha, Mouse CD11b monoclonal antibody (APC) (AGIM0551)
Supplier:	Assay Genie
Supplier-Nr:	AGIM0551